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The dataset thus provides a depth of neurocognitive phenotyping that is currently unparalleled, enabling integrative analyses of age-related changes in brain structure, brain function, and cognition, and providing a testbed for novel analyses of multi-modal neuroimaging data.

Your access to the NCBI website at gov has been temporarily blocked due to a possible misuse/abuse situation involving your site.

This is helpful in retrieving the copter if it is beyond your sight.

This cancer information summary provides an overview of the use of laetrile as a treatment for people with cancer.

The summary includes a history of laetrile research, a review of laboratory studies, the results of clinical trials, and possible side effects of laetrile use.

This summary contains the following key information: Many of the medical and scientific terms used in this summary are hypertext linked (at first use in each section) to the NCI Dictionary of Cancer Terms, which is oriented toward nonexperts.

is derived from the terms laevorotatory and mandelonitrile and is used to describe a purified form of the chemical amygdalin, a cyanogenic glucoside (a plant compound that contains sugar and produces hydrogen cyanide) found in the pits of many fruits and raw nuts and in other plants, such as lima beans, clover, and sorghum.[1-6] In body fluids and at physiological p H, hydrogen cyanide dissolves to form the cyanide anion. In the 1970s, laetrile gained popularity as an anticancer agent.

By 1978, more than 70,000 individuals in the United States were reported to have been treated with it.[2,7,8] Laetrile has been used for cancer treatment both as a single agent and in combination with a metabolic therapy program that consists of a specialized diet, high-dose vitamin supplements, and pancreatic enzymes.[9,10] In the United States, researchers must file an Investigational New Drug (IND) application with the U. Food and Drug Administration (FDA) to conduct drug research in human subjects.

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